In recent years, the Ho Lab has published research in a variety of academic journals, including the Journal of Neuro-Oncology and Nature Communications. Please see a featured selection of publications below.


New Developments in the Pathogenesis, Therapeutic Targeting, and Treatment of Pediatric Medulloblastoma

Fang FY, Rosenblum JS, Ho WS, Heiss JD.

Cancer (Basel). 2022 May 3; 14 (9): 2285. doi: 10.3390/cancers14092285.
PubMed Link >

Mitochondrial Dysfunction, Macrophage, and Microglia in Brain Cancer

Lu R, Ho W

Front Cell Dev Bio. 2021 Jan 15; 8: 620788. doi: 10.3389/fcell.2020.620788.
PubMed Link >

MRI-guided laser interstitial thermal therapy using the Visualase system and Navigus frameless stereotaxy in an infant: technical case report

Lee JJ, Clarke D, Hoverson E, Tyler-Kabara EC, Ho WS*

J Neurosurg Pediatr. 2021 May 21; doi: 10.3171/2020.11.PEDS20823. Epub ahead of print.
PubMed Link >

Targeting Mitochondrial Oxidative Phosphorylation in Glioblastoma Therapy

Wu Z, Ho WS, Lu R

Neuromolecular Med. 2022 Mar 1; 24 (1): 18-22. doi: 10.1007/s12017-021-08678-8. Epub 2021 Sep 6.
PubMed Link >

Inhibition of protein phosphatase-2A with PD-1 blockade enhances antitumor immunity and survival in glioblastoma

Maggio D, Ho WS*, Breese R, Walbridge S, Wang H, Heiss JD, Gilbert MR,Kovach JS, Lu R*, Zhuang Z*

J Neurooncol. 2020 Jun 1; 148 (2): 231-244. doi: 10.1007/s11060-020-03517-5.
PubMed Link >

Induction of Immune Response Against Metastatic Tumors via Vaccination of Mannan-BAM, TLR Ligands and Anti-CD40 Antibody (MBTA)

Medina R, Wang H, Caisová V, Cui J, Indig IH, Uher O, Ye J, Nwankwo A, Sanchez V, Wu T, Nduom E, Heiss J, Gilbert MR, Terabe M, Ho W, Zenka J, Pacak K, Zhuang Z

Adv Ther (Weinh). 2020 Sep 1; 3 (9): 2000044. doi: 10.1002/adtp.202000044. Epub 2020 Jun 9.
PubMed Link >

Small posterior fossa in Chiari I malformation affected families is significantly linked to 1q43-44 and 12q23-24.11 using whole exome sequencing

Musolf AM, Ho WSC, Long KA, Zhuang Z, Argersinger DP, Sun H, Moiz BA, Simpson CL, Mendelevich EG, Bogdanov EI, Bailey-Wilson JE, Heiss JD

Eur J Hum Genet. 2019 Oct 1; 27 (10): 1599-1610. doi: 10.1038/s41431-019-0457-7.. Epub 2019 Jun 21.
PubMed Link >

Toward a comprehensive view of cancer immune responsiveness: a synopsis from the SITC workshop

Bedognetti D, Ceccarelli M, Galluzzi L, Lu R, Palucka K, Samayoa J, Spranger S, Warren S, Wong KK, Ziv E, Chowell D, Coussens LM, De Carvalho DD, DeNardo DG, Galon J, Kaufman HL, Kirchhoff T, Lotze MT, Luke JJ, Minn AJ, Politi K, Shultz LD, Simon R, Thórsson V, Weidhaas JB, Ascierto ML, Ascierto PA, Barnes JM, Barsan V, Bommareddy PK, Bot A, Church SE, Ciliberto G, De Maria A, Draganov D, Ho WS, McGee HM, Monette A, Murphy JF, Nisticò P, Park W, Patel M, Quigley M, Radvanyi L, Raftopoulos H, Rudqvist NP, Snyder A, Sweis RF, Valpione S, Zappasodi R, Butterfield LH, Disis ML, Fox BA, Cesano A, Marincola FM

J Immunother Cancer. 2019 May 22; 7 (1): 131. doi: 10.1186/s40425-019-0602-4.
PubMed Link >

Complex Chiari malformation: using craniovertebral junction metrics to guide treatment

Ho WS, Brockmeyer DL

Childs Nerv Syst. 2019 Oct 1; 35 (10): 1847-1851. doi: 10.1007/s00381-019-04214-z. Epub 2019 May 28.
PubMed Link >

The Luckiest Girl in the World: Transpalatal penetration of the brain by a knitting needle without major injury

Matthew M, Newberry I, Ho W, Brockmeyer D, Smith M

Int J Pediatr Otorhinolaryngol Case Rep. 2019; (100670): doi: 10.1016/j.pedeo.2019.100670.
PubMed Link >

A comparison of the accuracy of fetal MRI and prenatal ultrasound at predicting lesion level and perinatal motor outcome in patients with myelomeningocele

Sherrod BA, Ho WS, Hedlund A, Kennedy A, Ostrander B, Bollo RJ

Neurosurg Focus. 2019 Oct 1; 47 (4): E4. doi: 10.3171/2019.7.FOCUS19450.
PubMed Link >

LB-100, a novel Protein Phosphatase 2A (PP2A) inhibitor, sensitizes malignant meningioma cells to the therapeutic effects of radiation

Ho WS, Sizdahkhani S, Hao S, Song H, Seldomridge A, Tandle A, Maric D, Kramp T, Lu R, Heiss JD, Camphausen K, Gilbert MR, Zhuang Z, Park DM

Cancer Lett. 2018 Feb 28; 415: 217-226. doi: 10.1016/j.canlet.2017.11.035. Epub 2017 Dec 2.
PubMed Link >

Pharmacological inhibition of protein phosphatase-2A, with novel inhibitor LB-100, achieves durable immune-mediated antitumor activity when combined with PD-1 blockade

Ho W, Wang H, Heiss J, Gilbert MR, Lu R

Nat Commun. 2018 May 29; 9 (1): 2126. doi: 10.1038/s41467-018-04425-z.
PubMed Link >

Severe cranial deformity following cerebrospinal fluid diversion in an adolescent with osteogenesis imperfecta

Ho WS, Jane JA

J Neurosurg Pediatr. 2018 Oct 1; 22 (4): 348-351. doi: 10.3171/2018.4.PEDS18109. Epub 2018 Jul 6.
PubMed Link >

PP2A inhibition with LB100 enhances cisplatin cytotoxicity and overcomes cisplatin resistance in medulloblastoma cells

Ho WS, Feldman MJ, Maric D, Amable L, Hall MD, Feldman GM, Ray-Chaudhury A, Lizak MJ, Vera JC, Robison RA, Zhuang Z, Heiss JD

Oncotarget. 2016 Mar 15; 7 (11): 12447-63. doi: 10.18632/oncotarget.6970.
PubMed Link >